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. 2020 Apr 10;10:6170. doi: 10.1038/s41598-020-63149-7

Table 2.

Demographics and characteristics of the non-diabetic subjects.

Non-Obese (n = 77) Obese (n = 60) p-value
Age 41.00 (31.00–52.00) 46.00 (33.75–56.00) 0.09
Gender (Male) 28 (36.4%) 24 (40.0%) 0.79
BMI 24.71 (22.46–26.86) 34.02 (31.60–36.16) <0.001
Waist/Hip Ratio 0.84 (0.79–0.89) 0.90 (0.82–0.97) <0.01
TC (mmol/L) 5.00 (4.35–5.75) 5.20 (4.60–5.90) 0.41
HDL (mmol/L) 1.36 (1.09–1.66) 1.17 (1.01–1.44) <0.05
LDL (mmol/L) 3.10 (2.50–3.90) 3.50 (2.80–3.85) 0.24
TGL (mmol/L) 0.81 (0.60–1.09) 1.12 (0.66–1.55) <0.05
FPG (mmol/L) 5.07 (4.80–5.47) 5.20 (4.90–5.80) <0.05
HbA1c (DCCT %) 5.50 (5.30–5.80) 5.70 (5.38–5.93) 0.08
Insulin (mIU/L) 7.71 (5.21–15.14) 15.43 (8.10–29.18) <0.001
Adiponectin (μg/mL) 4.88 (3.21–7.40) 4.07 (2.45–5.57) 0.06
Leptin (ng/mL) 5.19 (2.69–7.84) 10.07 (6.79–13.51) <0.001
PAI-1 (ng/mL) 13.05 (10.01–16.73) 15.65 (12.55–19.13) <0.01
IL-6 (pg/mL) 16.56 (13.19–19.77) 16.52 (14.17–20.89) 0.56
TNF alpha (pg/mL) 122.25 (104.67–160.75) 125.95 (102.36–141.80) 0.54
hsCRP(μg/mL) 1.06 (0.55–3.04) 3.07 (1.69–6.53) <0.001
Hypertension 8 (10.4%) 8 (13.3%) 0.79
Hyperlipidemia 6 (7.8%) 7 (11.7%) 0.64

Median (IQR) presented for continuous variables and N (%) presented for categorical variables. P values were calculated using Mann–Whitney U test for continuous variables and chi-squared test for categorical variables. BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; hsCRP, high sensitivity c-reactive protein; IL-6, interleukin-6; LDL, low-density lipoprotein; PAI-1, plasminogen activator inhibitor-1; TGL, triglycerides; TNF alpha, tumor necrosis factor alpha.