Table 3.
Demographics and characteristics of patients with type 2 diabetes.
| Non-obese (n = 36) | Obese (n = 65) | p-value | |
|---|---|---|---|
| Age | 55.00 (47.75–58.00) | 53.00 (49.00–57.00) | 0.95 |
| Gender (Male) | 20 (55.6%) | 34 (52.3%) | 0.92 |
| BMI | 27.21 (25.21–28.95) | 34.19 (32.67–35.72) | <0.001 |
| Waist/Hip Ratio | 0.93 (0.87–0.97) | 0.95 (0.91–1.02) | 0.08 |
| TC (mmol/L) | 4.50 (3.85–5.65) | 4.90 (4.02–5.82) | 0.47 |
| HDL (mmol/L) | 1.04 (0.90–1.21) | 1.11 (0.88–1.33) | 0.56 |
| LDL (mmol/L) | 2.75 (2.02–3.70) | 3.05 (2.09–3.90) | 0.91 |
| TGL (mmol/L) | 1.32 (0.80–1.90) | 1.38 (1.10–1.88) | 0.43 |
| FPG (mmol/L) | 6.70 (5.70–8.70) | 7.30 (6.40–10.40) | <0.05 |
| HbA1c (DCCT %) | 6.40 (5.90–7.60) | 8.15 (6.80–9.15) | <0.001 |
| Insulin (mIU/L) | 17.51 (8.95–31.03) | 15.49 (7.88–26.16) | 0.69 |
| Adiponectin (μg/mL) | 2.93 (1.94–3.87) | 3.33 (1.91–4.98) | 0.43 |
| Leptin (ng/mL) | 5.81 (3.14–8.10) | 7.85 (5.36–10.88) | <0.05 |
| PAI-1 (ng/mL) | 16.37 (14.92–20.98) | 13.85 (11.69–17.43) | <0.05 |
| IL-6 (pg/mL) | 18.47 (15.95–21.95) | 16.54 (13.96–20.27) | 0.15 |
| TNF alpha (pg/mL) | 140.41 (125.35–168.66) | 117.61 (105.84–146.38) | <0.01 |
| hsCRP(μg/mL) | 1.67 (0.74–4.75) | 3.59 (2.07–7.79) | <0.001 |
| Hypertension | 18 (50.0%) | 39 (60.0%) | 0.45 |
| Hyperlipidemia | 13 (36.1%) | 21 (32.3%) | 0.87 |
Median (IQR) presented for continuous variables and N (%) presented for categorical variables. P values were calculated using Mann–Whitney U test for continuous variables and chi-squared test for categorical variables. BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; hsCRP, high sensitivity c-reactive protein; IL-6, interleukin-6; LDL, low-density lipoprotein; PAI-1, plasminogen activator inhibitor-1; TGL, triglycerides; TNF alpha, tumor necrosis factor alpha.