Table 4.
Classification of results for gene knock-out simulation in different versions of embryo heart generated from iMM1865, min-iMM1865 and iMM1415 based on FBA and linear MOMA approaches.
| TP | FP | FN | TN | Sensitivity | Specificity | ||
|---|---|---|---|---|---|---|---|
| FBA method | iHeart1709 | 9 | 1 | 53 | 119 | 15% | 99% |
| iHeart1696 | 9 | 1 | 53 | 119 | 15% | 99% | |
| iHeart1653 | 13 | 2 | 49 | 118 | 21% | 98% | |
| min-iHeart1716 | 9 | 1 | 53 | 119 | 15% | 99% | |
| min-iHeart1703 | 9 | 1 | 53 | 119 | 15% | 99% | |
| min-iHeart1651 | 13 | 1 | 49 | 119 | 21% | 99% | |
| iHeart1041 | 9 | 5 | 40 | 68 | 18% | 93% | |
| iHeart1034 | 9 | 5 | 40 | 68 | 18% | 93% | |
| iHeart983 | 9 | 5 | 40 | 68 | 18% | 93% | |
| lMOMA method | iHeart1709 | 10 | 1 | 52 | 119 | 16% | 99% |
| iHeart1696 | 10 | 1 | 52 | 119 | 16% | 99% | |
| iHeart1653 | 14 | 2 | 48 | 118 | 23% | 98% | |
| min-iHeart1716 | 10 | 1 | 52 | 119 | 16% | 99% | |
| min-iHeart1703 | 10 | 1 | 52 | 119 | 16% | 99% | |
| min-iHeart1651 | 14 | 1 | 48 | 119 | 23% | 99% | |
| iHeart1041 | 9 | 5 | 40 | 68 | 18% | 93% | |
| iHeart1034 | 9 | 5 | 40 | 68 | 18% | 93% | |
| iHeart983 | 9 | 5 | 40 | 68 | 18% | 93% |
TP: True Positive, FP: False Positive, FN: False Negative, TN: True Negative.
Sensitivity= TP/(TP+FN), Specificity=TN/(TN+FP).