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. 2020 Apr 10;10:6169. doi: 10.1038/s41598-020-63263-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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MiRNAs associated with platelet reactivity in the TRILOGY-ACS cohort by serial real-time PCR array. A heatmap of miRNA expression levels against platelet reactivity units (PRU) at three distinct timepoints during the TRILOGY-ACS trial; baseline, 30 days and 6 months post-CVD event on P2Y₁₂ anti-platelet therapy. Bolded coefficients represent miRNA with p-values < 0.05. Regression analysis was performed using miRNA/PR data within individual time-points and was adjusted for clinical covariates.