Table 1.
Demographic and clinical characteristics of the study population.
| Clinical and laboratory findings | Optimal microbiota (N = 14) n (%) | Non-optimal Microbiota (N = 18) n (%) | P-value |
|---|---|---|---|
| Black race | 14 (100) | 18 (100) | |
| Median age in years (range) | 18.5 (16–20) | 19 (16–22) | p = 0.0001 |
| Chlamydia trachomatis (PCR positive) | 3 (21) | 3 (17) | p > 0.9999 |
| Neisseria gonorrhoeae (PCR positive) | 3 (21) | 0 (0) | p = 0.0734 |
| Trichomonas vaginalis (PCR positive) | 1 (7) | 0 (0) | p = 0.4375 |
| HSV-2 IgG positive | 0 (0) | 6 (0) | p = 0.0238 |
| PSA positive | 1 (7) | 8 (44) | p = 0.0443 |
| Using DMPA | 3 (21) | 2 (11) | p = 0.6313 |
| Using Nur-Isterate | 10 (71) | 12 (67) | p > 0.9999 |
| Using Implanon | 1 (7) | 4 (22) | p = 0.3547 |
PCR, polymerase chain reaction; PSA, prostate specific antigen; DMPA, depot medroxyprogesterone acetate. All participants were herpes simplex virus (HSV), Mycoplasma genitalium and Treponema pallidum PCR negative and did not have detectable yeast cells on Gram-stained vaginal smears. Mann-Whitney U test was used to compare continuous data and Fisher’s exact test was used for categorical data.