Figure 3.

Population dynamics of parasites within an infected human and an infected mosquito. (A) The number of parasites in an infected human host as a function of time after the infection of the human host (the time since the susceptible human got the infection from the infectious mosquito). The blue and red curves show the number of infected red blood cells and gametocytes with their standard deviations, respectively. (B) The number of sporozoites in an infected mosquito as a function of time since the infection of the mosquito (the time since the susceptible mosquito got the infection from the infectious human) with the standard deviation. (C) Simulation results showing the parasite dynamics in the human host under antimalarial drug treatment. The parasite density represents the percentage of the number of parasites compared to that at the treatment starting time. The open circle lines show the experimental data (adapted from³⁵), and the dashed lines show the simulation results.