Table 1.
A summary of the parameters and their values used in the within-host population dynamics model.
Definitions | Values | Refs. |
---|---|---|
Number of inoculated sporozoites via a mosquito bite | 10 sporozoites | 22 |
Production rate of merozoites from a sporozoite | 30,000 merozoites per 10 days | 22,23,34 |
Production rate of merozoites from an IRBC | 10 merozoites per 2 days | 24,25 |
Production rate of gametocytes from an IRBC | 10 gametocytes per 10 days | 46 |
Gametocyte to merozoite ratio | 0.1 | 26 |
Average gametocyte circulation time | 6.4 days | 26 |
Parasite carrying capacity | 1012 per host | 22 |
Gametocyte sex ratio (male:female) | 1:3.6 | 27 |
Parasite reduction ratio of artemisinin monotherapy | 103 | 47 |
Number of male gametes produced from a male gametocyte | 8 gametes | 24 |
Number of female gametes produced from a female gametocyte | 1 gamete | 24 |
Time from zygote to oocyst | 7 days | 29 |
Number of sporozoites produced from a mature oocyst | 10,000 sporozoites per 10 days | 30 |