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. 2020 Apr 5;13:2887–2897. doi: 10.2147/OTT.S239425

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© 2020 Yang et al.

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Overexpression of miR-34c sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity in vitro. (A) Transfection with miR-34c mimic (50 pmol/mL) increased the cellular level of miR-34c in the SKOV3 and A2780 cell lines. (B) Transfection with miR-34c (50 pmol/mL) increased the cytotoxicity of various concentrations of cisplatin in the SKOV3 and A2780 cell lines. (C) Effect of miR-34c on the IC50 of cisplatin in the SKOV3 and A2780 cell lines.

Notes: Data was expressed as mean±SD. *P<0.05.

Abbreviation: IC50, 50% inhibiting concentration.