Table 3.
Adjusted differences in selected health outcomes by isolated pathogen.
| Comparison | Estimate | ||
|---|---|---|---|
| Length of stay 1, days | Pathogen Isolated | Ratio of Geometric LS-Means (95% CI) | p-value 2 |
| MRSA (vs. none) | 1.35 (1.11–1.65) | <0.001 | |
| MRSA (vs. MSSA) | 1.26 (1.05–1.52) | <0.001 | |
| MRSA (vs. non-S. aureus) | 1.14 (0.91–1.42) | 0.43 | |
| MSSA (vs. non-S. aureus) | 0.90 (0.77–1.05) | 0.56 | |
| MSSA (vs. none) | 1.07 (0.90–1.27) | 0.73 | |
| Non-S. aureus (vs. none) | 1.19 (0.98–1.44) | 0.09 | |
| Re-admitted ≤60 days | Pathogen Isolated | Odds Ratio (95% CI) | p-value 2 |
| MRSA (vs. none) | 1.35 (0.26–7.09) | 0.97 | |
| MRSA (vs. MSSA) | 2.13 (0.48–9.51) | 0.56 | |
| MRSA (vs. non-S. aureus) | 0.83 (0.16–4.45) | 0.99 | |
| MSSA (vs. non-S. aureus) | 0.39 (0.07–2.27) | 0.52 | |
| MSSA (vs. none) | 0.63 (0.12–3.36) | 0.89 | |
| Non-S. aureus (vs. none) | 1.62 (0.45–4.98) | 0.92 | |
| Required PICU admission | Pathogen Isolated | Odds Ratio (95% CI) | p-value 2 |
| MRSA (vs. none) | 1.53 (0.32–7.32) | 0.90 | |
| MRSA (vs. MSSA) | 1.31 (0.43–4.01) | 0.92 | |
| MRSA (vs. non-S. aureus) | 1.10 (0.20–5.96) | 1.00 | |
| MSSA (vs. non-S. aureus) | 0.84 (0.15–4.75) | 0.99 | |
| MSSA (vs. none) | 1.16 (0.26–5.23) | 0.99 | |
| Non-S. aureus (vs. none) | 1.39 (0.20–9.64) | 0.97 | |
| Subperiosteal abscess | Pathogen Isolated | Odds Ratio (95% CI) | p-value 2 |
| MRSA (vs. none) | 6.40 (2.09–19.66) | <0.001 | |
| MRSA (vs. MSSA) | 1.26 (0.58–2.75) | 0.87 | |
| MRSA (vs. non-S. aureus) | 1.44 (0.52–3.97) | 0.80 | |
| MSSA (vs. non-S. aureus) | 1.14 (0.41–3.18) | 0.99 | |
| MSSA (vs. none) | 5.08 (1.72–15.05) | <0.001 | |
| Non-S. aureus (vs. none) | 4.46 (1.29–15.42) | 0.011 |
1 Length of stay was log-transformed due to non-normality. Estimates are ratios of back-transformed geometric least-squares (LS) means. 2 Tukey–Kramer adjusted for all pairwise comparisons. All models were adjusted for age, race, infection type (osteomyelitis only, septic arthritis only, and both), fever at presentation, WBC count, and infection severity (CRP). Bolded values indicate a statistically significant difference with a p-value less than 0.05. MRSA-Methicillin-resistant Staphylococcus aureus, MSSA-Methicillin-sensitive Staphylococcus aureus, PICU–pediatric intensive care unit, WBC–white blood cell, CRP–C-reactive protein.