Table 3.
Scales and Cytokine Concentration in Salivary Samples |
Statistic | Sample | ||
---|---|---|---|---|
DP (n = 35) | HMP (n = 26) | Pooled (n = 61) | ||
BDI-II (21 items) | ordinal α | 0.874 | 0.856 | 0.957 |
OHHS (8 items) | ordinal α | 0.802 | 0.913 | 0.861 |
OHIP-14-PD (14 items) | ordinal α | 0.912 | 0.936 | 0.923 |
IL-1β | r [95% CI] | 0.998 [0.994, 1] | ||
IL-6 | r [95% CI] | 0.999 [0.997, 1] | ||
MMP-8 | r [95% CI] | 0.972 [0.955, 1] |
Note. Sample: DP = dental patients with periodontitis, MHP = mental health patients with depressive symptomatology, and Pooled = union of the two patient samples. Scales: BDI-II = total score in Beck Depression Inventory-II, OHHS = total score in Oral Hygiene Habits Scale, and OHIP-14-PD = total score in the Oral Health Impact Profile applied to Periodontal Disease. Cytokines: IL-1β = salivary interleukin 1 beta concentration, IL-6 = salivary interleukin 6 concentration, and MMP-8 = salivary matrix metalloproteinase-8 concentration. Statistic: n = sample size, ordinal α = standardized coefficient alpha calculated from polychoric correlation matrix, r = Pearson’s product-moment correlation coefficient between eight levels of serial dilutions of the antibody concentration (0, 3.125, 6.25, 12.5, 25, 50, 100, and 200 pg/mL for IL-1β; 0.156, 3.125, 6.25, 12.5, 25, 50, and 100 pg/mL for IL-6; and 0, 78, 156, 313, 625, 1250, 2500, and 5000 pg/mL for MMP-8) and the average absorbance (negative of the logarithm with base 10 of quotient between incident and transmitted light intensities). Concentration and absorbance values are only available for each microplate; since the microplate of each cytokine test has 96 wells, both patient samples were joined and, therefore, correlations could only be calculated in the pooled sample. CI = confidence interval calculated through percentile bootstrapping method with the simulation of 1000 random samples.