Table 1.

The kinetic properties of each ADH class, population, and tissue distribution [23,29].

Gene Locus	Subunit	Km for Ethanol (mM)	Vmax (min−1)	Major Ethnicity	Tissue Distribution
Class I
ADH1B*1	β1	0.05	54	Caucasians, African-Americans	Liver, lung
ADH1B*2	β2	0.9	-	Asians
ADH1B*3	β2	34	-	African-Americans
ADH1C*1	γ1	1	-	All groups	Liver, stomach
ADH1C*2	γ2	0.63	-	Caucasians
Class II: ADH2	π	34	40		Liver
Class III: ADH3	χ	1000	-		Ubiquitous
Class IV: ADH4	σ, µ	20	1510		Stomach and esophagus

“-“: no data available.