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. 2020 Mar 4;8(3):50. doi: 10.3390/biomedicines8030050

Table 2.

Km for acetaldehyde and tissue distribution of human aldehyde dehydrogenase (ALDH) [23,29].

Gene Locus Km for Acetaldehyde Tissue Distribution
Class I ALDH1 30 µM Liver and many other tissues
Class II ALDH2 <1 µM Low levels in most tissues with the expression highest in liver compared to kidney and muscle
Class III ALDH3 11 mM Stomach, liver, cornea