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Time-kill curves for ertapenem, piperacillin-tazobactam, and fosfomycin against ESBL-producing E. coli isolates, CTX-M-15-producing A038 (ST131) and CTX-M-14-producing C046 (ST1193). (A and B), the results of 1× MICs of single antibiotics, (C and D), the results of 0.5× MICs of single and combination of antibiotics. ETM, ertapenem; P/T, piperacillin-tazobactam; FOS, fosfomycin.
