Figure 4.

Combined Impact of Comparative Fitness and Percent Prophylaxis Use: Here, we present a heat map representing the change in q-strain prevalence that occurs due to prophylaxis use and changes in comparative fitness. We demonstrate that increased prophylaxis use, and increased comparative fitness, both benefit the resistant strain. While the magnitude of the effect of increased relative fitness is observably greater, even when the relative fitness of q is low, the selective pressure imposed by prophylaxis use increases q-strain prevalence overall (we note that the lines appearing on the heat map are present for visual assistance only).