Table 3.
MIC, minimum bactericidal (or fungicidal) concentration (MBC/MFC) values for the three best antimicrobial extracts, determined by microdilution assays. Tested concentrations ranged from 7.8 µg/mL to 250 µg/mL.
| Micro-Organism | µg/mL | ||||||
|---|---|---|---|---|---|---|---|
| E2-2 | E2-3 | E2-4 | |||||
| MIC | MBC | MIC | MBC | MIC | MBC | ||
| Gram positive bacteria | Bacillus subtilis | 62.5 | NA | 125 | NA | 62.5 | 125 |
| Enterococcus faecalis ATCC 1034 | 62.5 | NA | 125 | NA | 62.5 | 250 | |
| Staphylococcus aureus NCTC 8325 | 62.5 | 250 | 62.5 | 250 | 62.5 | 125 | |
| Staphylococcus aureus CIP 53.154 | 31.2 | NA | 62.5 | NA | 62.5 | 125 | |
| Staphylococcus epidermidis | 31.2 | NA | 62.5 | NA | 62.5 | NA | |
| Listeria innocua | 31.2 | 125 | 125 | 250 | 62.5 | 125 | |
| Streptococcus pyogenes | 31.2 | NA | 7.8 | NA | 31.2 | NA | |
| Micrococcus luteus | 31.2 | 62.5 | 62.5 | NA | 62.5 | 250 | |
| Gram negative bacteria | Serratia marcescens | - | - | 62.5 | NA | - | - |
| Proteus vulgaris | 62.5 | NA | 31.2 | NA | - | - | |
| Providencia stuartii | 15.6 | NA | 125 | NA | - | - | |
| Pseudomonas aeruginosa ATCC 9027 | 31.2 | NA | 125 | 125 | - | - | |
| Shigella sonnei | 15.6 | NA | 250 | NA | 125 | NA | |
| MIC | MFC | MIC | MFC | MIC | MFC | ||
| Yeast | Candida glabrata | 31.2 | 125 | 125 | NA | 125 | NA |
| Candida tropicalis | 31.2 | NA | - | - | 31.2 | 250 | |
| Candida kefyr | 62.5 | 250 | 125 | NA | 62.5 | 250 | |
| Candida albicans | 62.5 | 125 | - | - | 125 | 125 | |
| Cryptococcus neoformans | 125 | NA | 125 | NA | 62.5 | NA | |
NT: Non tested; NA: No activity. Green boxes: MIC <100 µg/mL; Red boxes: 100 µg/mL< MIC; Yellow boxes: MBC of MFC detected.