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. 2016 Oct 14:127–164. doi: 10.1016/B978-0-12-801814-9.00005-2

Table 5.2.

Applications of Network Pharmacology

Traditional medicine
  • Scientific evidence for use of Ayurvedic medicine

  • Understanding the rationale of traditional formulations

  • Understanding the mechanism of action of Ayurvedic medicines

  • Safety and efficacy of Ayurvedic medicines

  • Possible substitutes for endangered botanicals

  • Network-based designing and prescribing of plant formulations

  • Analysis of multiple bioactives, studying synergistic action

  • Botanical biomarkers for quality control

Pharmacology
  • To develop new leads from natural products

  • Understanding the mechanism of action of drugs

  • Determining the possible side effects of drugs

  • Predicting new indications

  • Predicting toxicity

  • Predicting possible drug–drug interactions

  • Rational design of drugs based on group of interacting proteins

  • Drug repurposing

Drug research
  • Identifying novel drug targets

  • Reduced cost and time through in silico evaluation

  • Understanding the signaling pathway of disease types

  • Designing experiments based on drugs and targets

  • Therapeutics for multigene-dependent diseases

  • Discovery of disease-causing genes

  • Diagnostic biomarkers

  • Studying drug resistance or antibiotic resistance