Table 2.

Syndromic Panels that Are Currently Available in the United States for the Detection of Upper Respiratory Tract Pathogens

Analyte	FDA Cleared?	Adenovirus	Adenovirus Subtyping	Bordetella bronchiseptica	Bordetella holmesii	Bordetella pertussis/B. parapertussis	Chlamydophila pneumoniae	Coronavirus HKU1	Coronavirus NL63	Coronavirus 229E	Coronavirus OC43	Enterovirus/Rhinovirus	Human Bocavirus	Human Metapneumovirus	Human Metapneumovirus Subtyping	Human Parainfluenza Virus 1	Human Parainfluenza Virus 2	Human Parainfluenza Virus 3	Human Parainfluenza Virus 4	Influenza A	Influenza A Subtyping	Influenza B	Legionella pneumophila	Mycoplasma pneumoniae	Respiratory Syncytial Virus	Respiratory Syncytial Virus Subtyping
ePlex RP	+	+	−	−	−	−/−	+	+	+	+	+	+	−	+	−	+	+	+	+	+	+	+	−	+	+	+
eSensor RVP	+	+	+	−	−	−	−	−	−	−	−	+c	−	+	−	+	+	+	−	+	+	+	−	−	+	+
FilmArray RP Panel	+	+	−	−	−	+/−	+	+	+	+	+	+	−	+	−	+	+	+	+	+	+	+	−	+	+	−
FilmArray RP2 Panel	+	+	−	−	−	+/+	+	+	+	+	+	+	−	+	−	+	+	+	+	+	+	+	−	+	+	−
FilmArray RP EZa	+	+	−	−	−	+/−	+	+	+	+	+	+/+	−	+	−	+	+	+	+	+	+	+	−	+	+	−
NxTAG RPPb	+	+	−	−	−	−/−	+	+	+	+	+	+	+	+	−	+	+	+	+	+	+	+	−	−	+	+
VERIGENE RP Flexb	+	+	−	+	+	+/+	−	−	−	−	−	+c	−	+	−	+	+	+	+	+	+	+	−	−	+	+

Abbreviations: FDA, US Food and Drug Administration; RPP, respiratory pathogen panel.

Symbols: +, yes or present on panel; -, no or absent from panel.

^aThe FilmArray RP EZ assay tests for human coronaviruses HKU1, NL63, 229E, and OC43 and human parainfluenza viruses 1, 2, 3, and 4, but it reports those analytes as coronavirus and parainfluenza virus, respectively.

^bThe NxTAG and VERIGENE RP flex assays allow users to selectively report targets.

^cRhinovirus alone is reported by the eSensor RVP, VERIGENE RP flex, US versions of the NxTAG RVP assays.