Table II.

Vertical and Longitudinal Sites of Replication and Villous Atrophy in the Intestine for Porcine Coronaviruses and Group A Rotaviruses

		Longitudinal		Vertical small intestine (site)		Villous atrophy small intestine		Respiratory tract
Virus	Diarrhea	Small intestine	Colon	Villous	Crypt	Site	Extent	Upper	Lower	Reference
Coronavirus
Virulent TGEV	Severe	D,J,I	–	+ Entire	–	D,J,I	Severe	±	±	Frederick et al. (1976)
Attenuated TGEV	Mild/none	J,I	–	+ Entire	–	J,I/none	Mild	+	±	Frederick et al. (1976) Furuuchi et al. (1979)
PRCV	None	–	–	– NA	–	None	None	+	+	Pensaert and Cox (1989)
Rotavirus
Group A	Mild-severe	D,J,I	±	+ Entire	–	J,I	Moderate-severe	−	−	Theil et al. (1978)