Table III.
Comparison of Intestinal and Respiratory ASC Responses and Protective Immunity Induced by TGEV and PRCV Strains in Neonatal Pigs at Postchallenge Day (PCD) 0 and 4a
| Mean No. ASC/5 ⊠ 105 MNC at PCD 0 |
Mean No. ASC/5 ⊠ 105 MNC at PCD 4 |
Percent protection against TGEV challenge |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Virus inoculum group | Intestinal lamina propria | Bronchial lymph node | Intestinal lamina propria | Bronchial lymph node | Diarrhea (%) | Shedding (%) | ||||||||
| IgG | IgA | G/Ab | IgG | IgA | G/A | IgG | IgA | G/A | IgG | IgA | G/A | |||
| Virulent TGEV | 109 | 620 | 0.18 | 25 | 1 | 25 | 15 | 109 | 0.14 | 300 | 94 | 3.2 | 100 | 80 |
| PRCV | <1 | 1 | UD | 223 | 1 | 223 | 150 | 4 | 38 | 320 | 7 | 46 | 58 | 17 |
| Controls | <1 | <1 | — | <1 | <1 | — | <1 | <1 | — | <1 | <1 | — | 10 | 22 |
a
Data summarized from VanCott et al. (1994).
b
G/A, ratio of IgG to IgA ASCs; UD, undetermined because numerator <1.