Table 3.

Adverse event incidence.

Adverse event n (%)	Total N = 193	Control N = 99	Treated N = 94
Edema of both lower limbs	3 (1.6)	0 (0)	3 (3.2)
Hypokalemia	1 (0.5)	0 (0)	1 (1.1)
Facial edema	1 (0.5)	1 (1.0)	0 (0)
Hematuria	1 (0.5)	1 (1.0)	0 (0)
Trunk and limb pruritus	1 (0.5)	0 (0)	1 (1.1)
Renal contusion	1 (0.5)	0 (0)	1 (1.1)
Blood pressure elevation	2 (1.0)	0 (0)	2 (2.1)
Transaminase elevation	1 (0.5)	1 (1.0)	0 (0)

Adverse events include abnormal clinical laboratory test results, physical examination, and physiological test results.