Table 8.
Anti-inflammatory activity of the crude extract on carrageenan-induced paw edema.
| Treatment group | The paw volume (ml), mean ± SEM | ||||
|---|---|---|---|---|---|
| Basal | 1 h | 2 h | 3 h | 4 h | |
| Control | 0.182 ± 0.01 | 0.180 ± 0.008 | 0.202 ± 0.014 | 0.203 ± 0.01 | 0.213 ± 0.008 |
| Indomethacin | 0.167 ± 0.008 | 0.137 ± 0.004a2 | 0.107 ± 0.003a3 | 0.088 ± 0.007a3 | 0.070 ± 0.004a3 |
| 100 mg/kg extract | 0.195 ± 0.008 | 0.155 ± 0.008 | 0.150 ± 0.004a2b2c2 | 0.117 ± 0.005a3b1 | 0.100 ± 0.004a3b2c1 |
| 200 mg/kg extract | 0.193 ± 0.012 | 0.152 ± 0.008 | 0.128 ± 0.008a3 | 0.100 ± 0.004a3 | 0.085 ± 0.002a3 |
| 400 mg/kg extract | 0.178 ± 0.012 | 0.147 ± 0.005a1 | 0.107 ± 0.004a3 | 0.092 ± 0.005a3 | 0.078 ± 0.005a3 |
Note. Values are expressed as mean ± SEM (n = 6 mice in each group) and analyzed by one-way ANOVA followed by the post hoc Tukey test; acompared to the negative control; bcompared to indomethacin; ccompared to 400 mg/kg; 1P < 0.05; 2P < 0.01; 3P < 0.001.