Table 2.
Select investigations in which EIS officers have participated, 1951–2006
| 1951–60 |
| • Contamination of killed poliovirus vaccine with live virus |
| • Asian influenza epidemics |
| • Nosocomial staphylococcal epidemics |
| • Childhood lead poisoning from peeling paint |
| 1961–70 |
| • Cases of poliomyelitis associated with oral vaccine |
| • Smallpox epidemics through 1977 |
| • Hong Kong influenza epidemics |
| • Hurricane Camille after-effects |
| • Salmonellosis in commercially produced chicken |
| 1971–80 |
| • Salmonella associated with pet turtles |
| • Oyster-associated hepatitis |
| • Bacteremia from contaminated intravenous fluids |
| • Childhood lead poisoning from environmental exposure |
| • Norwalk virus epidemic |
| • Vinyl chloride-associated liver cancer |
| • Legionnaires' disease |
| • Ebola virus in Zaire and Sudan |
| • Guillain-Barré syndrome associated with swine influenza vaccine |
| • Toxic shock syndrome associated with tampon use |
| • Heat wave-associated morbidity and mortality in Missouri |
| • Aspirin-associated Reye's syndrome |
| • National Study of the Efficacy of Nosocomial Infection Control (SENIC) |
| • National cancer and steroid hormone study |
| • Investigation of the health effects of the Three Mile Island nuclear incident (Pennsylvania) |
| • Health effects of the Mount Saint Helens volcano eruption (Washington state) |
| • Health effects of exposure to chemicals from an abandoned toxic waste site at Love Canal (New York) |
| 1981–90 |
| • Human immunodeficiency virus and acquired immunodeficiency syndrome |
| • Acne medication Isotretinoin is associated with birth defects |
| • Escherichia coli O157:H7 associated with hemorrhagic diarrhea and hemolytic uremic syndrome |
| • Role of parvovirus in erythema infectiosum (Fifth disease) |
| • Toxic oil syndrome in Spain |
| • Eosinophilia-myalgia syndrome |
| • Clusters of suicides by teenagers |
| • Vietnam War veterans health studies |
| • Mercury poisoning from commercial paint |
| 1991–2000 |
| • Multistate outbreak of E. coli O157:H7-associated diarrhea and hemolytic uremic syndrome from hamburgers |
| • Hantavirus pulmonary syndrome |
| • Health after-effects of Hurricane Andrew |
| • Cryptosporidiosis from contaminated public drinking water in Milwaukee (Wisconsin) |
| • Acute renal failure in Haiti from acetaminophen contaminated with diethylene glycol |
| • Impact of physician-assisted suicide in Oregon |
| • Multistate outbreak of salmonellosis associated with commercial ice cream |
| • Suicide after natural disasters |
| • Rotavirus vaccine recall |
| • West Nile virus epidemic |
| • Cardiac valvulopathy associated with fenfluramine and phentermine (fen-phen) |
| • Violence against mothers of newborns from unintended pregnancies |
| • Definition of excessive weight gain in pregnancy |
| 2001–06 |
| • Aftermath of World Trade Center and Pentagon terrorist attacks and anthrax mailings |
| • Monkeypox |
| • Severe acute respiratory syndrome (SARS) |
| • Health effects of Hurricanes Katrina and Rita |
| • Multistate outbreaks of E. coli and Salmonella associated with eating raw vegetables |
| • Multiple investigations of the obesity epidemic |
Adapted from Thacker SB, Dannenberg AL, and Hamilton DH (2001) Epidemic Intelligence Service of the Centers for Disease Control and Prevention: 50 years of training and service in applied epidemiology. American Journal of Epidemiology 154: 987.