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. 2013 Sep 18:1610–1620. doi: 10.1016/B978-0-7216-9654-6.50166-1

TABLE 163-5.

Representative Immune Factors in Human Milk the Production of Which Is Delayed in the Recipient Infant

Agents Time of Maturation
Secretory IgA ∼4–12 mo
Full antibody repertoire ∼2 yr
Memory T cells ∼2 yr
Lysozyme ∼1–2 yr
Lactoferrin ?
Interferon-γ ?
Interleukin-6 ?
Interleukin-8 ?
Interleukin-10 ?
TNF-α ?
PAF-acetylhydrolase ?

PAF-AH = platelet activating factor-acetylhydrolase; TNF-α = tumor necrosis factor-α