Fig. 2.

αCD40/ICB efficacy is independent of innate immune sensors but requires Batf3 and CD40 expression. (A–E) Wild-type mice or mice lacking the indicated gene were implanted with s.c. PDA and treated as in SI Appendix, Fig. S1A, as indicated. For waterfall plots, each bar represents a single mouse. For growth curves, each point represents the mean of n = 5 to 10 mice and error bars indicate the SEM. For survival curves, each dot represents the death or censoring of a single mouse. **P < 0.01, ***P < 0.001, and ****P < 0.0001; ns indicates not significant.