Table 41.1.
Cellular Sites of Replication and Assembly of Selected Virus Families
| Virus Family | Envelope | Site of Replication and Neocapsid Assembly | Site of Budding (for enveloped viruses) |
|---|---|---|---|
| RNA viruses | |||
| Arenavirus | + | Cytoplasm | Plasma membrane |
| Bunyavirus | + | Cytoplasm | Golgi complex |
| Coronavirus | + | Cytoplasm | Rough endoplasmic reticulum |
| Orthomyxovirus | + | Nucleus and cytoplasm | Plasma membrane |
| Paramyxovirus | + | Cytoplasm | Plasma membrane |
| Picornavirus | − | ||
| Calicivirus | − | Cytoplasm | |
| Astrovirus | − | Cytoplasm | |
| Reovirus | − | Cytoplasm | |
| Retrovirus | + | Nucleus and cytoplasm | Plasma membrane |
| Rhabdovirus | + | Cytoplasm | Plasma membrane |
| Filovirus | + | Cytoplasm | Plasma membrane |
| Togavirus | + | Cytoplasm | Plasma membrane |
| Flavivirus | + | Cytoplasm | Endoplasmic reticulum |
| DNA viruses | |||
| Adenovirus | − | Nucleus | |
| Herpesvirus | + | Nucleus | Nuclear envelope |
| Hepadnavirus | + | Nucleus | Endoplasmic reticulum |
| Papillomavirus | − | Nucleus | |
| Parvovirus | − | Nucleus | |
| Polyomavirus | − | Nucleus | |
| Poxvirus | + | Cytoplasm/plasma membrame | Cytoplasm |