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. 2009 Feb 17:500–518. doi: 10.1016/B978-012373944-5.00314-X

Figure 4.

Figure 4

Schematic representation of HRV genome and polyprotein organization. Diagram of the RNA genome with VPg protein, the 5′ untranslated region (5′UTR), the protein coding region, the 3′UTR, and the poly(A) tail (top). Processing pattern of rhinovirus polyprotein. Proteases 2Apro and 3Cpro cleave the polyprotein, generating P1, P2, and P3 precursors (bottom). All intermediate and final cleavages are carried out by 3Cpro and its precursor, 3CDpro, except for the VP0 peptide cleavage into VP4 and VP1, which is done by an as yet unknown protease.