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Schematic coronavirus structure. The virions are spherical, with an envelope containing a prominent crown (‘corona’) of peplomers of S (spike) glycoprotein. HE (hemagglutinin), E (small envelope protein), and M (membrane glycoprotein). The genome is a positive-stranded RNA associated with the N (nucleocapsid phosphoprotein), composing the helical RNP (ribonucleoprotein).
