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. 2013 Oct 10:303–349. doi: 10.1016/B978-0-7020-4979-8.00008-X

Table 8.1.

Differential diagnosis of ‘diarrhoea’ in rabbits

Syndrome Incidence in pet rabbits Hard faeces Caecotrophs Condition of rabbit Causes
Uneaten normal caecotrophs (soft odorous faecal material that looks like diarrhoea to the owner) Common Copious quantities of hard faecal pellets Normal consistency Well
Appetite good
Obesity
Dental disease
Spondylosis
Arthritis
Perineal dermatitis etc.
Uneaten soft caecotrophs Common Copious quantities of hard faecal pellets Soft, liquid consistency Well Change of diet
Lack of dietary fibre
Succulent foods
Stress
+ same causes as uneaten normal caecotrophs
Coccidiosis Rare in adult
Common in juvenile
Diarrhoea can range from haemorrhagic liquid faeces to bulky soft faeces Indistinguishable from hard faeces Depends on severity of condition Eimeria spp.
Mucoid enteropathy Rare in adult
Associated with stress
Sporadic outbreaks in juveniles
Normal hard faeces are absent
Mixed or interspersed mucus and diarrhoea
No faecal output
in later stages
Abnormal soft caecotrophs may be intermittently interspersed with mucus and diarrhoea May be eating in early stages
Bloated appearance
Progresses to inappetence and tooth grinding
Still unclear
Dysautonomia has been found in some cases
Caecal impaction Sporadic incidence Absence of hard faeces None in later stages May pick at food in early stages Appears to be associated with pain or stress
Can produce mucus, which owners mistake for diarrhoea Caecal impaction is also part of mucoid enteropathy complex
Can be caused by ingestion of materials that are moved into the caecum, absorb water and are not broken down by caecal microflora. Examples include clay litter, methylcellulose or other bulk laxatives
Enteritis Rare in adults
Enteritis caused by bacterial overgrowth/imbalances is more common in the suckling or growing rabbit
Normal hard faeces are absent
Liquid diarrhoea
Not seen Unwell
Anorexic
May crave fibre
Bacterial or viral pathogens such as E. coli, clostridia, rotaviruses
Can be induced by antibiotics
Plant toxins
Enterotoxaemia Sporadic cases in adult rabbits
More common in juveniles
Liquid faeces that may be tarry
Rabbit may die before diarrhoea develops
Not seen Unwell
Rapidly progressive
May be collapsed
Clostridial species
Can be induced by antibiotics
Chronic inflammatory disease Rare
Only adults
Large amounts of bulky soft faeces Indistinguishable from hard faeces Thin, bloated
Periods of ravenous appetite interspersed with periods of anorexia
Not known
? immune mediated
Sometimes associated with adhesions? post spay

In other species, diarrhoea is manifested by the frequent evacuation of watery droppings (Blood and Studdert, 1999). Rabbits produce two types of droppings, i.e. hard faeces and caecotrophs. Normal caecotrophs are soft in consistency and are often mistaken for diarrhoea. The nature and frequency of both types of faeces are an important consideration. In some conditions, there is also excessive mucus production that can be mistaken for diarrhoea.