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Multi-omics data integration via the SPACiAL method. Left: Islet of Langerhans with immunohistochemical staining (glucagon in red, insulin in green). Middle: Spatial distribution of 3-O Sulfogalactosylceramide (m/z 778.5147). Right: Data integration via SPACiAL, utilizing the IHC stainings to automatically identify alpha cells (semi-transparent, pixelated staining in red) and correlating metabolites. Lateral MALDI resolution (pixel): 15 μm.
