Table 4.
Simple and multiple non-mixture model analysis of survival of patients with colorectal cancer (2008–2016)
| Variable | Simple |
Multiple |
|||
|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | ||
| Age | <60 y | 1 | - | 1 | - |
| ≥ 60 y | 1.04 | 0.74-1.45 | 0.96 | 0.65-1.41 | |
| Sex | Female | 1 | - | 1 | - |
| Male | 1.05 | 0.75-1.47 | 1.07 | 0.72-1.58 | |
| BMI | Obese | 0.53 | 0.24-1.16 | 0.34 | 0.12-0.97 |
| Overweight | 0.90 | 0.61-1.33 | 0.86 | 0.56-1.33 | |
| Normal | 1 | - | 1 | - | |
| Underweight | 1.09 | 0.65-1.84 | 1.06 | 0.61-1.84 | |
| Residual tumor after chemo-radio therapy | No | 1 | - | 1 | - |
| Yes | 1.08 | 0.59-1.96 | 1.73 | 0.75-3.98 | |
| Staging | 0 | 1 | - | 1 | - |
| I | 1.14 | 0.58-2.30 | 1.86 | 0.72-4.79 | |
| II (A,B,C) | 1.12 | 0.55-2.27 | 1.59 | 0.63-3.98 | |
| III (A,B,C) | 1.53 | 0.79-3.07 | 1.8 | 0.44-7.53 | |
| Type of surgery | Conversion | 1 | - | 1 | - |
| Laparoscopy | 0.81 | 0.39-1.69 | 0.74 | 0.33-1.66 | |
| Laparotomy | 1.48 | 0.71-3.10 | 1.47 | 0.65-3.31 | |
| N-stage | N0 | 1 | - | 1 | - |
| N1 | 1.41 | 0.98-2.03 | 1.32 | 0.45-3. 9 | |
| T-stage | T0 | 1 | - | - | - |
| T1 | 1.20 | 0.63-2.31 | - | - | |
| Size of tumor | < 3.5 cm | 1 | - | - | - |
| ≥ 3.5 cm | 1.10 | 0.77-1.58 | - | - | |
| Vascular invasion | No | 1 | - | - | - |
| Yes | 1.34 | 0.59-3.06 | - | - | |
| Neural invasion | No | 1 | - | - | - |
| Yes | 1.67 | 0.77-3.49 | - | - | |
| Lymphatic invasion | No | 1 | - | - | - |
| Yes | 1.46 | 0.62-2.75 | - | - | |
HR= Hazard Ratio; CI= Confidence Interval; P-value for overall multiple non-mixture model=0.046