Table 3.
Homocysteine levels before and after treatment according to MTHFR C677T genotype
CC (n = 10) | CT (n = 55) | TT (n = 97) | P value* | |
---|---|---|---|---|
HCY before treatment, μmol/L | 20.26 ± 6.60 | 18.90 ± 6.37 | 21.75 ± 8.19 | 0.049 |
HCY after treatment, μmol/L | 14.02 ± 3.53 | 12.98 ± 5.01 ab | 19.45 ± 11.32 ab | 0.002 |
P value** | 0.535 | 0.328 | 0.211 |
* Analysis of variance was used for comparison among genotypes
** Paired sample t-test was used for comparison between baseline and 1 month after treatment
ab Different letters indicate statistical significance. Least significant difference (LSD) test was used for pairwise comparison. CCvsCT p = 0.816; CC vs TT p = 0.215; CT vs TT p = 0.001