Table 3.

Evaluation of select drug candidates against B. henselae biofilm-recovered cells after drug exposure at different times

Drugs (5 μg/ml)	CFU per mL after drug exposure
	2 day	4 day	6 day
Drug free control	1.3 ± 0.2 × 1010	1.8 ± 0.2 × 1010	2.6 ± 0.3 × 1010
Azithromycin	4.5 ± 0.3 × 109	5.2 ± 0.3 × 109	9.3 ± 0.2 × 105
Cefuroxime	5.6 ± 0.3 × 109	2.3 ± 0.2 × 109	1.7 ± 0.1 × 106
Ciprofloxacin	3.2 ± 0.3 × 108	2.5 ± 0.3 × 108	5.1 ± 0.3 × 102
Daptomycin	9.8 ± 0.2 × 109	3.4 ± 0.3 × 109	2.7 ± 0.2 × 106
Disulfiram	6.1 ± 0.3 × 109	4.6 ± 0.3 × 109	3.8 ± 0.3 × 107
Doxycycline	5.3 ± 0.3 × 109	3.8 ± 0.1 × 109	6.2 ± 0.3 × 105
Gentamicin	6.2 ± 0.3 × 109	5.8 ± 0.2 × 109	8.1 ± 0.3 × 102
Methylene blue	8.9 ± 0.4 × 109	6.8 ± 0.2 × 109	2.3 ± 0.2 × 102
Miconazole	9.8 ± 0.3 × 109	2.2 ± 0.1 × 1010	1.6 ± 0.1 × 1010
Nitrofurantoin	4.3 ± 0.1 × 109	3.6 ± 0.2 × 109	2.8 ± 0.2 × 109
Rifampin	5.6 ± 0.2 × 109	4.8 ± 0.3 × 109	3.2 ± 0.2 × 102
SXT	7.8 ± 0.3 × 109	6.4 ± 0.3 × 109	2.7 ± 0.2 × 109
Azithromycin+Ciprofloxacin	4.1 ± 0.2 × 109	5.8 ± 0.3 × 106	0
Azithromycin+Methylene blue	6.8 ± 0.2 × 109	5.2 ± 0.3 × 105	0
Rifampin+Ciprofloxacin	7.6 ± 0.2 × 109	4.7 ± 0.2 × 109	0
Rifampin+Methylene blue	5.9 ± 0.1 × 109	4.8 ± 0.2 × 109	0