Table 2.
Meta-analysis results of all available studies in measured outcomes
| Measured outcomes | Subgroup | No. studies | No. patients | Heterogeneity test | Model | RR/WMD | 95% CI | P | Begg’s test | Egger’s test | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| I2(%) | P | Pr > |z|* | Pr > |z|** | P > |t|* | ||||||||
| Preoperative cholangitis | Total | 9 | 813 vs. 622 | 19.1 | 0.273 | Random | 0.46 | 0.34, 0.62 | < 0.001 | 0.404 | 0.466 | 0.73 |
| HCC | 2 | 145 vs. 53 | 81.5 | 0.02 | Random | 0.5 | 0.19, 1.3 | 0.156 | -- | -- | -- | |
| DBO | 4 | 535 vs. 439 | 17.4 | 0.259 | Random | 0.38 | 0.26, 0.57 | < 0.001 | 0.174 | 0.308 | 0.282 | |
| Preoperative pancreatitis | Total | 7 | 750 vs. 508 | 0 | 0.929 | Fixed | 0.69 | 0.50, 0.95 | 0.023 | 0.881 | 1 | 0.551 |
| HCC | 2 | 145 vs. 53 | 0 | 0.999 | Fixed | 0.67 | 0.30, 1.47 | 0.314 | -- | -- | -- | |
| DBO | 3 | 485 vs. 367 | 0 | 0.825 | Fixed | 0.74 | 0.50, 1.12 | 0.152 | 0.602 | 1 | 0.603 | |
| Stent dysfunction rate | Total | 6 | 464 vs. 437 | 38.6 | 0.149 | Random | 0.58 | 0.43, 0.8 | 0.001 | 0.188 | 0.26 | 0.311 |
| HCC | 2 | 145 vs. 53 | 0 | 0.319 | Random | 0.48 | 0.35, 0.67 | < 0.001 | -- | -- | -- | |
| DBO | 2 | 204 vs. 291 | 26.3 | 0.244 | Random | 0.59 | 0.39, 0.90 | 0.015 | -- | -- | -- | |
| Morbidity | Total | 5 | 231 vs. 188 | 0 | 0.418 | Fixed | 0.77 | 0.64, 0.93 | 0.007 | 0.142 | 0.221 | 0.163 |
| POPF | Total | 3 | 170 vs. 160 | 7.7 | 0.338 | Fixed | 0.65 | 0.45, 0.92 | 0.016 | 0.602 | 1 | 0.536 |
HCC hilar cholangiocarcinoma; DBO distant biliary obstruction; POPF postoperative pancreatic fistula; No.number of; RR risk ratio; WMD weighted mean difference; CI confidence interval
*P value
**P value (continuity corrected)
--Not applicable