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. 2017 Sep 1:37–52. doi: 10.1016/B978-0-12-803109-4.00004-0

Figure 4.9.

Figure 4.9

Plaque assays are used to count infectious particles. Samples are diluted and aliquots of each dilution are added to cultured cells. The cells are covered with an agaroseoverlay. Virus produced from an infected cell can infect nearby cells. If infected cells are killed, a region free of cells (the plaque) develops.