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Organization of murine BALT. Lungs from mice infected with influenza 12 days previously were frozen in OCT medium and sectioned on a cryostat. Sections were probed with antibodies to B220 (blue), CD3 (red), and CD11c (green). Note the presence of three B220+ B cell follicles, two of which are underneath a major airway. CD3+ T cell zones are between the follicles and some T cells are scattered in the follicles. CD11c+ DCs are located primarily in the T cell zones.
