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Liposomes labeled with one of two interacting peptides fuse on mixing. (A) The two peptides are linked to DOPE via a PEG linker. (B) The two peptides associate to form a coiled coil which colocalizes the liposomes leading to fusion. (C) Comparison between the reduced SNARE model on the left and the natural process on the right.
Reproduced with permission from Robson Marsden et al.63 copyright Wiley-VCH Verlag GmbH & Co. KGaA (2009).
