Table I.

Approximate Physiologic Values for Guinea Pigs ^a, ^b, ^c, ^d, ^e, ^f

General data
Body weight: adult male	900–1000 gm
Body weight: adult female	700–900 gm
Birth weight	60–115 gm
Body surface aread,g,h	700–830 gm: 9.2 (wt in gm)2/3 cm2 200–680 gm: 10.1 (wt in gm)2/3 cm2
Rectal temperaturei	37.2–39.5°C
Diploid numberi–j	64
Life span: usual	3–4 years
Life span: extreme	6–7 years
50% survival	60 months
Food consumption	6gm/100gm body weight/day
Water consumption	10 ml/100 gm body weight/day
Gastrointestinal transit timek	13–30 hr
Critical temperaturei	30°C
Thermal neutrality rangei	2–31°C
Cardiovascular and respiratory systemsl, m, n, o
Respiratory rate	42–104/min
Tidal volume	2.3–5.3 ml/kg body weight
Oxygen use	0.76–0.83ml/gm body weight/hr
Plasma C02	18–26mM/liter
C02 pressure	21–59 mm Hg
Plasma pH	7.17–7.53
Heart rate	230–380/min
Blood volume	69–75 ml/kg body weight
Cardiac outputp	240–300ml/min/kg body weight
Blood pressure	80–94/55–58 mm Hg
Blood cellsp–q
Erythrocytes	5.4 × l06mm3 ± 12%r
Hematocrit	43 ± 12%
Hemoglobin	13.4gm/dl ± 12%
MCV	81μm3
MCH	25 pg
MCHC	30%
Leukocytes	9.9 × 103/mm3± 30%
Neutrophils	28–44%
Lymphocytes	39–72%
Kurloff cells	3–4%
Eosinophils	1–5%
Monocytes	3–12%
Basophils	0–3%
Platelets	250–850 × 103/mm3
Clinical chemistry (serum)c, d, e
Total protein	4.5–5.9gm/dl
Albumin	2.3–3.0 gm/dl
Globulin	1.7–2.6 gm/dl
Glucose	80–110mg/dl
Blood urea nitrogen	15.7–31.5 mg/dl
Creatinine	1.0–1.8mg/dl
Total bilirubin	0.2–0.4mg/dl
Lipids	95–240 mgVdl
Phospholipids	25–75 mg/dl
Total triglyceride	28–76 mg/dl
Cholesterol	20–43 mg/dl
Calcium	9.0–11.3 mEq/dl
Phosphorus	4.2–6.5 mEq/dl
Magnesium	2.1–2.7 mg/dl
Sodium	121–126 mEq/liter
Potassium	4–6mEq/liter
Chloride	96–98 mEq/liter
Alanine aminotransferase	31–51 IU/liter
Alanine transaminase	32–51 IU/liter
Alkaline phosphatase	68–71 IU/liter
Aspartate aminotransferase	38–57 IU/liter
Aspartate serum transaminase	38–58 IU/liter
Creatine phosphokinase	80–130 IU/liter
Lactate dehydrogenase	37–63 IU/liter

^aFesting (1976b).

^bCharles River Breeding Laboratories (1982).

^cAltman and Dittmer (1974).

^dWhite and Lang (1989).

^eClifford and White (1999).

^fHarkness and Wagner (1995).

^gHong et al. (1977).

^hKlaassen and Doull (1980).

ⁱShort and Woodnott (1969).

^JRobinson (1971).

^kJilge (1980).

^lSchalm et al.(1975).

^mSisk (1976).

ⁿPayne et al. (1976).

^oSchermer (1967).

^pQvuWec et al. (1977).

^qLaird (1974).

^rCoefficient of variation.