Table 18-20.

Antihypertensive Drugs

	DOSAGE
GENERIC NAME	DOG	CAT
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS
Enalapril	0.5 mg/kg PO q12-24h	0.25-0.5 mg/kg PO q12-24h
Captopril	0.5-2.0 mg/kg PO q8-12h	3.1-6.25 mg/cat PO q8-12h
Lisinopril	0.5 mg/kg PO q24h	—
Benazepril	0.25-0.5 mg/kg PO q24h	0.25-0.5 mg/kg PO q24h
CALCIUM CHANNEL BLOCKERS
Diltiazem	0.5-1.5 mg/kg PO q8-12h to maximum of 200 mg/day	1.75-2.4 mg/kg q8h
Diltiazem sustained release	10 mg/kg PO q24h	10 mg/kg PO q24h
Amlodipine	0.1 mg/kg PO q24h or 2.5 mg/dog	0.625-1.25 mg/cat PO q24h
β-ADRENERGIC BLOCKERS
Propranolol	0.2-1 mg/kg PO q8 to maximum of 200 mg/day	0.4-1.2 mg/kg PO q8h or 2.5-5 mg/cat PO q8-12h
Atenolol	0.2-2 mg/kg PO q12-24h or 6.25-12.5 mg/dog PO q12h	2-3 mg/kg PO q12h or 6.25-12.5 mg/cat PO q12h
β-ADRENERGIC BLOCKERS
Prazosin	0.065 mg/kg (1 mg/15 kg) PO q8-12h	0.065 mg/kg (1 mg/15 kg) PO q8-12h
Phenoxybenzamine	0.2-1.5 mg/kg PO q8-12h	2.5-7.5 mg/cat PO q8-12h or 0.5 mg/kg PO q12h
VASODILATORS
Hydralazine	0.5-2 mg/kg PO q12h	2.5 mg/cat PO q12-24h
Nitroprusside	1-10 μg/kg/min IV CRI	1-10 μg/kg/min IV CRI
DIURETICS
Chlorothiazide	20-40 mg/kg PO q12-24h	20-40 mg/kg PO q12-24h
Hydrochlorothiazide	2-4 mg/kg PO q12h	2-4 mg/kg PO q12h
Furosemide	1-4 mg/kg PO, IM, IV or SC q8-12h (or as needed)	1-4 mg/kg PO, IM, IV or SC q8-24h

CRI, Constant infusion rate.