Figure 3.12.

(A) Avian influenza virus infection in the respiratory tract of a chicken. The normal side-by-side position of columnar epithelial cells has been replaced by cuboidal cells without cilia, several of which exhibit massive virus budding from their apical surface. Thin-section electron microscopy. Magnification: ×10,000. (B, C) Scanning electron micrographs showing desquamating cells in an influenza-virus-infected mouse trachea and the adherence of Pseudomonas aeruginosa. Bar: 2 μm. (B) Normal mouse trachea showing a single bacterium (arrow) on a serous cell. (C) Microcoliny of P. aeruginosa adhering to a residual epithelial cell on an otherwise denuded surface.

[B, C: Courtesy of P. A. Small, Jr.]