Table I.

Commonly Used Rat Strains

Inbred strains	Usefulness as models
ACI	Congenital genitourinary anomalies, prostatic adenocarcinomas
BB/Wor	Juvenile insulin-dependent diabetes mellitus
BN (Brown Norway)	Inducible, transplantable myeloid leukemia, hydronephrosis, bladder carcinoma
BUF (Buffalo)	Spontaneous autoimmune thyroiditis, host for transplantable Morris hepatoma
COP (Copenhagen)	Prostate adenocarcinoma
F-344 (Fischer 344)	Inbred rat model for National Toxicology Program's
	Carcinogen Bioassay Program and the National
	Institute on Aging
LEW (Lewis)	Multiple sclerosis, various experimentally induced autoimmune diseases
LOU/C	Myeloma, production of IgG autoantibody
SHR (spontaneous hypertensive rat)	Hypertension, cardiovascular research
WF (Wistar-Furth)	Mononuclear cell leukemia
Zucker	Obesity
Mutant strains	Characteristics
Brattleboro	Diabetes insipidus (autosomal recessive)
Gunn	Jaundice, kernicterus (autosomal recessive)
Nude	T cell deficient (autosomal recessive)
Obese SHR	Type 4 hyperlipoproteinemia (autosomal recessive)