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Invasive adenocarcinoma of prostate.
(A) Hematoxylin and eosin (H&E) of invasive adenocarcinoma of prostate. By H&E alone, the differential diagnosis includes invasive adenocarcinoma and adenosis. (B) High-molecular-weight cytokeratin immunostain of invasive adenocarcinoma of prostate. Loss of high-molecular-weight cytokeratin (34βE12) immunoreactivity around the glands of interest supports a diagnosis of invasive adenocarcinoma.
