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. 2016 May 6:111–132. doi: 10.1016/B978-0-12-800947-5.00007-7

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© 2016 Jennifer Louten

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Figure 7.6 — Cytopathic effects of viral infection.

Viruses cause a variety of visible effects upon cells. (A) Human herpesvirus-6 infection causes ballooning of infected cells. (Image courtesy of Zaki Salahuddin and the National Cancer Institute.) (B) These photos show the cytopathic effects upon cells before (left) and after (right) infection with murine cytomegalovirus. Note the differences in morphology and organization of the cells. (C) A multinucleate syncytium caused by SARS-CoV in a histological section of stained human lung. (Image courtesy of the CDC/Dr. Sherif Zaki.) (D) A cytoplasmic inclusion body composed of viral proteins and nucleic acid is visible in this electron micrograph of a cell infected with Lagos bat virus. Note the bullet-shaped virions assembling from the inclusion body. (Image courtesy of Dr. Fred Murphy and Sylvia Whitfield at the CDC.)