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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Semin Oncol Nurs. 2019 Nov 19;35(6):150960. doi: 10.1016/j.soncn.2019.150960

Table 2.

Selected conditioning chemotherapy and TBI regimens prior to HCT for treatment of leukemia

Regimen Drugs Days of Cycle relative to day of transplant (Day 0) Myeloid or Lymphoid Leukemia
Flu-Bu-Cy (low dose) Fludarabine, Busulfan, Cyclophosphamide Flu −7 to −2
Bu −7 to −4
Cy −3 to −2		 Myeloid
Flu-Mel-Thio Fludarabine, Melphalan, Thiotepa Thio −7
Mel −6
Flu −5 to −2		 Myeloid or Lymphoid
Thio-Flu-Bu Thiotepa, Fludarabine, Busulfan Thio −6 to −5
Flu −4 to −2
Bu −4 to −2		 Myeloid
Flu-Cy-TBI Fludarabine-Cyclophosphamide-Total Body Irradiation Flu −6 to −2
Cy-6 to −5
TBI −1		 Lymphoid
Flu-TBI (reduced intensity) Fludarabine-Total Body Irradiation Flu −4 to −2
TBI −1		 Myeloid

Selected regimens reproduced from Gyurkocza (2014).12

Cycle days obtained from Shabbir-Moosajee et al. (2015),15 and Jethava et al. (2017).17