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Overexpression of Per2 suppresses tumorigenesis of OSCC in vivo. (A) The tumor volume and weight of mice in the Per2-OE group were markedly lower than those in the NC group (N=3). (B) The growth curve of the subcutaneous tumors displayed that the tumors in the Per2-OE group grew more slowly. Data are presented as the mean ± SD (n ≥ 3). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
