Figure 1.

LncRNAs and mRNAs expression profiles in breast cancer. A. Volcano plot, where the two vertical lines are the 2-fold change boundaries and the horizontal line is the statistical significance boundary (p < 0.05). Genes with fold change ≥ 2 and statistical significance are marked with red dots. B. Heat map and hierarchical clustering of lncRNA profile comparison between the breast cancer and paired normal breast samples. Each row represents one lncRNA, and each column represents one tissue sample. The relative lncRNA expression is depicted according to the color scale. Red indicates up-regulation and green indicates down regulation. The numbers 2.0, 0 and -2.0 are folds changes in the corresponding spectrum.