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. 2020 Mar 13;11(12):3424–3432. doi: 10.7150/jca.40233

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Enhanced expression of miR-425 correlates with downregulation of DKK3 expression in BC samples. (A) Immunohistochemical staining of DKK3 in normal bladder tissues, NMIBC tissues and MIBC tissues. (B,C) QRT-PCR analysis of DKK3 and miR-425 mRNA expression in human BC tissues from 32 patients. (D) A two-tailed Pearson's correlation analysis reveals that the mRNA expression of miR-425 is inversely correlated with the expression of DKK3. (E) Box plots represent relative expression of miR-425 in NMIBC tissues and MIBC tissues. (F) Box plots represent relative expression of miR-425 in BC tissues and adjacent normal tissues.