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. 2020 Mar 4;10(10):4334–4348. doi: 10.7150/thno.42982

Figure 2.

Figure 2

miR-128 is an important regulator of osteoclastogenesis in BMMs. A Mature mmu-miR-128 expression upon RANKL-induced osteoclastogenesis. Data is depicted in terms of mean ± SD. **P < 0.01 by one-way ANOVA with Tukey' s post hoc test. B RANKL-induced osteoclast differentiation for three days in transfected BMMs containing either miR-128 mimic/inhibitor or control mimic/inhibitor. TRAP staining was performed. Scale bars: 200 μm. C Osteoclast size and number. TRAP-positive cells with at least three nuclei were designated to be osteoclasts. Data is depicted in terms of mean ± SD. **P < 0.01 by one-way ANOVA with Tukey' s post hoc test. D qRT-PCR of mRNA expression of Nfatc1, Traf6, Ctsk, c-Fos, and c-Src. Data is depicted in terms of mean ± SD. **P < 0.01 by one-way ANOVA with Tukey' s post hoc test.