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. 2020 Mar 15;10(10):4466–4480. doi: 10.7150/thno.42478

Figure 2.

Figure 2

SR9009 induced remarkable apoptosis in SCLC cells. (A-D) SCLC cells were dose-dependently treated with SR9009 for 48 h. (E-F) H69AR and H446DDP cells were time dependently treated with 10 µM SR9009. (G-J) SCLC cells were concentration-dependently treated with SR9009 for 48 h. Densitometric values were quantified using the ImageJ software and normalized to control. The values of control were set to 1. The data are presented as means ± SD of three independent experiments. (K-N) Induction of apoptosis by indicated concentration of SR9009 is shown by cleaved caspase 3 and TUNEL staining for 72 h in SCLC cells (K, 10µM; L, 5µM; M, 20µM; N, 10µM). A typical result from 3 independent experiments is presented.