Figure 7.

Bifurcation Diagrams and Landscape Change upon Regulating VEGF->SOD and SOD->p53 Strength

(A) Bifurcation diagrams with regulation of VEGF->SOD.

(B) Bifurcation diagrams with regulation of SOD->p53.

(C) Landscape at ${\gamma }_{VEGF->SOD}$ = 1.3.

(D) Landscape at ${\gamma }_{VEGF->SOD}$ = 1.8.

(E) Landscape at ${\gamma }_{SOD->p53}$ = 3.4.

(F) Landscape at ${\gamma }_{SOD->p53}$ = 4.4. Solid line: In (A) and (B), blue, red, and yellow solid lines represent normal, cancer glycolysis, and cancer intermediate steady state, respectively. Colored dashed lines represent unstable steady states.