Table 2. The top 10 (a ranking by P-value from Metascape) biological process of DEGs in HCC.
| Term | Description | Count | Log10(P-value) |
|---|---|---|---|
| Upregulated | |||
| GO:0000819 | Sister chromatid segregation | 9 | −7.78 |
| GO:0000070 | Mitotic sister chromatid segregation | 8 | −7.31 |
| GO:0051301 | Cell division | 13 | −7.03 |
| GO:0000280 | Nuclear division | 11 | −6.90 |
| GO:0098813 | Nuclear chromosome segregation | 9 | −6.58 |
| GO:0140014 | Mitotic nuclear division | 9 | −6.54 |
| GO:0048285 | Organelle fission | 11 | −6.48 |
| GO:0016137 | Glycoside metabolic process | 4 | −6.26 |
| GO:0007059 | Chromosome segregation | 9 | −5.85 |
| GO:0033044 | Regulation of chromosome organization | 9 | −5.63 |
| Downregulated | |||
| GO:0032787 | Monocarboxylic acid metabolic process | 50 | −35.48 |
| GO:0071466 | Cellular response to xenobiotic stimulus | 26 | −25.28 |
| GO:0009410 | Response to xenobiotic stimulus | 30 | −24.68 |
| GO:0016054 | Organic acid catabolic process | 28 | −22.88 |
| GO:0046395 | Carboxylic acid catabolic process | 28 | −22.88 |
| GO:0044282 | Small molecule catabolic process | 33 | −22.53 |
| GO:1901615 | Organic hydroxy compound metabolic process | 35 | −22.21 |
| GO:0006805 | Xenobiotic metabolic process | 21 | −21.89 |
| GO:0008202 | Steroid metabolic process | 29 | −21.88 |
| GO:0006631 | Fatty acid metabolic process | 29 | −20.04 |
Notes.
Abbreviations
- DEGs
- differentially expressed genes
- HCC
- hepatocellular carcinoma
- GO
- gene ontology