Skip to main content
. 2020 Apr 8;8:e8930. doi: 10.7717/peerj.8930

Table 2. The top 10 (a ranking by P-value from Metascape) biological process of DEGs in HCC.

Term Description Count Log10(P-value)
Upregulated
GO:0000819 Sister chromatid segregation 9 −7.78
GO:0000070 Mitotic sister chromatid segregation 8 −7.31
GO:0051301 Cell division 13 −7.03
GO:0000280 Nuclear division 11 −6.90
GO:0098813 Nuclear chromosome segregation 9 −6.58
GO:0140014 Mitotic nuclear division 9 −6.54
GO:0048285 Organelle fission 11 −6.48
GO:0016137 Glycoside metabolic process 4 −6.26
GO:0007059 Chromosome segregation 9 −5.85
GO:0033044 Regulation of chromosome organization 9 −5.63
Downregulated
GO:0032787 Monocarboxylic acid metabolic process 50 −35.48
GO:0071466 Cellular response to xenobiotic stimulus 26 −25.28
GO:0009410 Response to xenobiotic stimulus 30 −24.68
GO:0016054 Organic acid catabolic process 28 −22.88
GO:0046395 Carboxylic acid catabolic process 28 −22.88
GO:0044282 Small molecule catabolic process 33 −22.53
GO:1901615 Organic hydroxy compound metabolic process 35 −22.21
GO:0006805 Xenobiotic metabolic process 21 −21.89
GO:0008202 Steroid metabolic process 29 −21.88
GO:0006631 Fatty acid metabolic process 29 −20.04

Notes.

Abbreviations

DEGs
differentially expressed genes
HCC
hepatocellular carcinoma
GO
gene ontology